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Useful Active Ingredients in Products to Combat Hair Loss

Hair loss is a very common and prevalent issue affecting most of us at some stage in our lives. Have you ever wondered what makes a hair loss product effective?

Here are certain active ingredients that you should look out for:

Minoxidil

Minoxidil was first formulated as a blood pressure medication and was coincidentally found to aid in hair growth. Topical minoxidil, in the form of sprays or foam formulations, has become a commonplace treatment for androgenetic alopecia in both men and women. Minoxidil shortens the telogen or hair shedding phase, while causing a prolonged anagen or hair growth phase, and increases hair follicle size at the same time.

Ketoconazole

Ketoconazole is a powerful anti-fungal and anti- inflammatory medication. When used in hair shampoos, ketoconazole helps to address antifungal conditions of the scalp, such as dandruff and seborrhoeic dermatitis. It is also useful to note that ketoconazole has anti- androgenic properties. It works by inhibiting an enzyme that converts testosterone to dihydrotestosterone (DHT). With the reduction of DHT, hair loss process will be delayed.

Baicapil

Baicapil, which can be found in Radium’s Self Defence Scalp Rejuvenation Serum, is a combination of three plant- based ingredients, such as scutellaria baicalensis (an extract from the root of the purple-flowered plant Baikal Skullcap), soy, and wheat sprouts. All these work synergistically to reduce hair loss and stimulate hair growth. In some clinical studies[1,2], Baicapil was shown to prolong the anagen phase (hair growth phase) in the hair growth cycle, thus leading to increased hair density.

There are many other useful active ingredients to look out for, such as saw palmetto, a fruit extract to prevent the effects of DHT responsible for androgenetic alopecia, caffeine to stimulate the hair follicles, as well as tea tree oil which helps to control sebum production in addition to antibacterial and anti-fungal properties.

Whatever it is, it is important to remember that hair loss is a multifactorial condition that may require a combination treatment approach using oral medications, topical products and hair regrowth treatments administered in clinic for best results.

References:

  1. Kamoji S G, Ashwini P, Nayak J (2018) A Study to Evaluate the Efficacy of Baicapil Formulations in Treatment of Telogen Effluvium. Int J Clin Expl Dermatol.
  2. Shin SH, Bak SS, Kim MK, Sung YK, Kim JC (2014) Baicalin, a flavonoid, affects the activity of human dermal papilla cells and promotes anagen induction in mice. Naunyn Schmiedebergs Arch Pharmacol.

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